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Argumentative Essay Topics In Medical Field
Thursday, September 3, 2020
Comparative analysis Essay Example | Topics and Well Written Essays - 750 words
Similar examination - Essay Example This sonnet is an extremely profound sonnet, one needs to peruse it and over again to comprehend its concealed significance. Life is truly muddled and we have to comprehend our point and to do that we have to plunk down and introspect. Numerous a period we run over circumstances in life where we need to settle on troublesome decisions and these troublesome decisions additionally choose our future, this sonnet is tied in with picking the street which is less voyage, it likewise goes to show the boldness of the artist who chooses to take a way which is less voyage and there is a chance of him getting lost yet he is sufficiently valiant to take a stab at something else from others. This is the thing that life is about, we should be sufficiently daring to run a way less voyaged, it might end up being an off-base choice or it might end up being a correct choice, it is tied in with settling on decisions when you are at the intersection, this is the thing that the sonnet is about. At the en d the writer considers over his decision, his life would have been entirely different had he taken the other street and this is valid. Our life would likewise be diverse had we settled on various choices and had we taken the street less voyaged, life is tied in with making the right, the best individuals regularly settle on the correct decisions. Proposal Statement: The sonnet has shrouded importance in it; the exacting significance of the sonnet is exceptionally straightforward. A voyager arrives at an intersection and is confused in light of the fact that the street shows the explorer two decisions, the voyager after much reasoning, picks the street less went by individuals. The metaphorical significance of the sonnet reflects upon the decisions that we make in our lives. We can either pick a street which is every now and again picked by others or we can decide to stroll on a street which is not really picked by others. Subsequent to settling on our decision, we would consistently have laments in light of the fact that the street not taken would consistently compel us to consider the unlimited prospects. This is the thing that the sonnet is about and this sonnet is extremely famous, Robert Frost turned into an easily recognized name in light of this sonnet. Abstract Devices: Antithesis is very obvious in the sonnet, the explorer needs to settle on his decision and he before long understands that he can just pick one way, the voyager wishes he could travel both however before long understands this isn't conceivable. Another scholarly gadget in the sonnet is representation, the street has been exemplified. ââ¬Å"All reasonable individuals realize that streets don't think, and along these lines don't need. They can't. Be that as it may, the portrayal of the street needing wear is a case of representation in this sonnet. A street really needing some as an individual would. In any case: some accept this to be mistaken and think needing wear isn't an embodiment, yet rather more seasoned English signifying lacking. So it would be On the grounds that it was green and needed wear; (The Road not Taken) The tone of the sonnet is bleak, words like ââ¬Å"sorryâ⬠and ââ¬Å"sighâ⬠have been utilized and these words reflect anguish. Verbal incongruity is additionally another hyperbole in this sonnet, the speaker realizes that when he thinks back and recalls, he should recount to his story with a ââ¬Å"sighâ⬠and he would likewise need to illuminate the distinctions the subsequent street would have made had he picked it. End: The street not taken is a sonnet with a concealed significance, it discloses to us how our life presents two decisions before us, when we settle on our decision, following a couple of years we as a general rule consider over the alternatives we would have had, had we decided to run out and about not taken. The sonnet is extremely precarious and requires tremendous focus to
Saturday, August 22, 2020
Police Personality free essay sample
There are two kinds of character characteristic assignments that are utilized to depict cops. The two kinds are the special qualities perspective, and socialization and experience perspective. The individuals who have confidence in the special qualities perspective are regularly alluded to as inclination character characteristics. Additionally in this perspective, it demands that law implementation pulls in a particular sort of individual to the activity. Inside this perspective, a portion of the characteristics included are tyranny, negativity, prejudice, threatening vibe, mystery, and devotion. (Dantzker, 2003). These are the kind of characteristics that law requirement organizations and security organizations don't wish to have. The other perspective, socialization and experience, otherwise called word related character, proposes that these character characteristics are created through the socialization and encounters of policing. The two perspectives can be powerfully contended. One of a kind Traits Normally turning into a cop naturally makes an individual a power figure, dictatorship is an appropriate individual component. It isn't hard to accept that such an individual may have tyrant propensities and wish to grow them by turning into a cop. We will compose a custom paper test on Police Personality or on the other hand any comparative subject explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page To contend that the individual ready to wear an identification, weapon, nightstick, and binds and to be legitimately accused of the ability to remove freedom, or in certain occasions life, doesn't have some level of a tyrant trademark under the watchful eye of entering law implementation appears to be absurd. (Dantzker, 2003) Socialization and Experience Although the information stay constrained, existing proof contends that distinguished character attributes, for example, pessimism, prejudice, and antagonistic vibe are the consequence of the policing experience. A few people even propose that the socialization procedure starts before the individual really turns into a cop. In either see, the tyrant attribute, if previous, is fortified through the police understanding. At the point when the cop puts on an identification and weapon, that feeling of power is improved many occasions over. There is no uncertainty a terrorizing factor in the policing job permits the legitimate trademark to develop. It has been contended that dictatorship and pessimism are appropriate pieces of the police character. With respect to being previous, the tyranny is commonly worthy, yet the skepticism isn't. (Dantzker, 2003) Conclusion It gives the idea that specific character qualities do exist among cops. Studies have been conflicting in deciding if these characteristics preexist or become some portion of the official through socialization. (Dantzker, 2003) I accept that the two characteristics are normal. I feel that every individual has one of a kind attributes that we are raised with. I additionally imagine that as we grow up and create we keep on changing those attributes which we have learned. I don't concur/can't help contradicting either. Be that as it may, I do firmly accept that relying upon which vocation we may pick those characteristics can change with socialization and experience. Interestingly, ââ¬Å"What may separate the cop from the non military personnel is his chance to realize his oblivious wishes through the truth of his activity, an open door scarcely any regular folks may haveâ⬠. Regardless of whether a police character type is previous or created, a significant component of the officerââ¬â¢s character is their demeanor.
Friday, August 21, 2020
Literature Review Domain Generated Algorithms Computer Vs Human
Question: Talk about theLiterature Reviewfor Domain Generated Algorithms Computer Vs Human. Answer: Presentation: This is the writing survey of the exploration venture in regards to the human created space name calculation and PC produced area calculation. This examination is about the connection between the human and PC. Around there, web is most significant factor as it is the primary network to the world through the PC innovation. Space name framework is the base of the web innovation. So as to utilize the web innovation proficiently, the area name calculation is significant, on the grounds that the activities of the web innovation depends on the space name framework, of the sites. In this specific situation, the productivity of the human created area name and the PC produced space calculation should be comprehended. Numerous scientists have worked around there in various sorts of strategies. In this writing audit, seven diverse research articles have been investigated to break down the two sorts of area name age calculations. Recognizing Algorithmically Generated Malicious Domain Names Yadav et al. (2010), led look into work in regards to the DNS based area fluxing. They have centered in the region of order and control where every one of the Bot questions needs to enroll for one space name just among the accessible area names. They have looked at the examples of the area names of the human created calculation and that of the PC produced calculations. As per them the alphanumeric characters produced in the space name framework are the most significant parts and need to have the principle center while building up the area name calculations. Ongoing botnets like Torping, Kraken and Conflicker have been examined in the exploration work to comprehend the malware in the space name framework. In the testing time frame, the specialists have checked the space names haphazardly. So as to direct the examination work in the zone of the area age calculations, he comprehension of the pernicious space names is the most significant truth. This article will assist with revealing th e region of understanding the noxious space names by the various sorts of the area age calculations. Along these lines, the survey will assist with understanding the proficiency of the human and PC produced space age calculations for distinguishing the pernicious areas. Discovering Domain-Generation Algorithms by Looking at Length Distributions The point of the scientist in this investigation was to discover the malware, which utilizes the space fluxing for going around the area name boycotting. This technique is helpful for creating the space age calculations. In this exploration paper, the analyst has said about the system for finding DGAs from Domain Name Service (DNS) question information. To distinguish certain malware that are liable for avoiding boycott use area dispersion. There are sure strategies used to make an inventive Domain age calculation (DGA) to discover the spaces created by the utilization of calculations. This exploration is being done to discover the DGAs from the information question of Domain Name Service (DNS). This framework discovers the IP address with dispersion which appears to be bizarre of string lengths of second-level. This examination paper characterizes the unidentified DGAs and the systems used to discover these calculations. In the accompanying technique, consequences of five days of ca lculation looking is done after which the conclusive outcome has been incorporated (Mowbray Hagen, 2014). By discovering the IP locations of the space produced calculations, gives security to the arbitrary DNS and IP addresses by giving exceptionally less measure of data about the area names. This article survey additionally helps in navigating the informational indexes and discovering the unidentified area names from the given arrangement of DNS with the goal that it very well may be recognized from distinguished areas. Since this calculation is mechanized it runs in a time span with little pieces of schedule openings. This framework additionally helps in finding the areas in an enormous arrangement of information with various dates. Story Generation with Crowd Sourced Plot Graphs Li et al. (2013), satiated about the story age calculation for the space name framework. . It is exorbitant and comprehensive to make such space arrangements physically as they are not adaptable. So this arrangement of story creation recognizes the right plan even in the unidentified spaces to give an account story (Li et al., 2013). This framework additionally makes the area tests from the characterized space of the model. A study of immense number of factors shows this mechanized framework makes preferred stories over undeveloped human essayists. This is the eventual fate of man-made reasoning in which the framework can make unending number of stories with a given arrangement of names, spots, characters and situations. This framework likewise incorporates the Scheherazade System of novel creation with an anecdotal story on the theme gave by the client. This framework utilizes publicly supporting which separates a mind boggling work into various basic assignments. Another strategy u tilized in Plot Graph realizing which is a determination technique for different stories with the reference of which numerous new stories can be made. The survey of this article will assist with breaking down the proficiency of a specific calculation in the territory of the exploration subject. Could an Algorithm Write a Better News Story Than a Human Reporter? As per Levy (2016), led investigate deal with improvement of a site required diverse calculation and furthermore a few kinds of area. He likewise gave center around how these calculation and areas are influencing the adaptability of the improvement of legitimate site by a designer. In this specific research article, it is discovered that programming language and composing is known as calculation which is not the same as the ordinary words and perusing done by the person by and large. It additionally recognized that huge number calculation is fundamentally accessible according to the interest however it isn't likewise fulfilling the exertion given by the human for its turn of events. The programmed account age in the cutting edge innovation industry is making new revaluation (Levy, 2016). These days organizations are utilizing a few weight identified with budgetary income and projection as calculation which is described in the arrangement of mechanical language for controlling the ref erenced database. The age of calculation and common language generators are likewise getting perplexing because of the distinction between the counterfeit call and the human insight. There are a few rich spaces like account, sports and detailing related required new programming mechanical stage to show their propelled designs, which will assist with understanding the effectiveness between the human and the PC calculation. In the event that an Algorithm Wrote This, How Would You Even Know? As per the exploration article composed by Podolny (2015), is started the following and portraying the Botnets by utilizing consequently produced areas for making a specific sites handing-off on the cutting edge space age calculations. There are a few calculations which are naturally produced from the area age calculation by concentrating on the DNS traffic dependent on botnets correspondence abilities. For the most part all the frameworks has been utilized in reality settings, though it is steady for the analysts to gauge the insight of and made spaces which is has a place with botnets consequently. The assessment and modernization of the 1,153,516 areas are material for the naming the right botnet at the same time. There are various methodologies which is given advising that confined AGD which is useful for production of DGA (Podolny, 2015). While improvement of and space for a site having a few provokes identified with DGA displaying, information assortment challenges and other ab sence of grounded realities. As indicated by the general research study, it is assessed that improvement in the following and checking of a DGA and CC framework is required. There are a few impediments which is recognized and precluded by the phoenix as needs be. This article survey will assist with understanding the advantages and restrictions of the PC produced calculation, which is significant for the exploration work in regards to the human created and PC produced area name calculations. Following and Characterizing Botnets Using Automatically Generated Domains There are many research papers proposed to help recognize whether a calculation can improve precise revealing stage than an individual dependent on the measure of mix-ups. A Chicago based organization has been chosen to deal with the circle for preferable online item over printing physical articles in the market. The online posted articles are worked on a few sites and article distributer and with the help of this organization can give better news administrations and others (Schiavoni et al., 2013). According to the various specialists and media discharged it is played out that the story science class is fundamentally made based on altering the exclusive man-made brainpower stage for changing over the narratives and articles. The account science is essentially identified with every single viewpoint whether it is identified with monetary situation, verifiable situation or others. According to the Hammond it is clarified that such sort of diaries and articles essentially utilized for n atural pecking order, money related information sharing and others data sharing exercises through the mode of innovation. This article is useful for understanding the effectiveness of the PC created calculations which is a significant area of the momentum look into work. Programmed Extraction of Domain Name Generation Algorithms from Current Malware Extraction of Domain name age calculations naturally from the executing malware is another arrangement of security utilized on the web. This is finished by sending botnets who help in secret activities or spamming as well as answerable for Di
Friday, June 12, 2020
The Value of Internships
à Note: This past summer our Oklahoma office had the pleasure of hosting three college interns who traveled from all over the country to join our team. One of them, Jacob Mauser, reflected on his experiences working as an intern, both abroad and in Oklahoma. We hope you enjoy his thoughts on his experiences. If you know any high school or college students, share this piece with them. It may inspire them to find their own internships next summer. At the beginning of July two years ago, I loosened the straps on my backpack and, letting it slip to the floor, collapsed into a new bed. It was only three in the afternoon in Pluderhausen, Germany, but Iââ¬â¢d been carrying a fair chunk of my life on my back for the better part of two days, and jetlag had hit hard around lunchtime. I closed my eyes and fell into a slumber so deep that I missed dinner that evening and breakfast the next day as well. It was an inauspicious start to my first true solo travel experience, to say the least. In a few days I would begin working at my employerââ¬â¢s factory, helping with small tasks and picking up some German. I had no idea what the future would hold. Two years later, I now sit in the conference room of IEWââ¬â¢s Bixby office, focusing on product photography and various writing projects. The blinds are open to let in the mid-afternoon sun. Through the open front door, a cool breeze blows, carrying the scent of the fields next door. If I were to remove my headphones, the sounds of nature would fill my ears. A cool day in late July is a rare thing, and even while we work, we take full advantage of this momentous occasion. In my mind now, that summer so long ago and this summer seem so far apart. Two years, five thousand miles, and a host of life-changing experiences separate these two summers, yet I know that they are linked together more intimately than I can possibly imagine. My experience working in a factory has little bearing on my work today, but it taught me how to adapt quickly to new tasks, a skill that has been vital. Pluderhausen is an ocean away from Bixby, but living out of a suitcase for a month in Germany taught me how to pack my life away into only a few bags, to carry the comforts of home with me where I go, and to avoid splurging on unnecessary souvenirs. Most important of all, however, have been the connections I have formed. Iââ¬â¢ve never directly used the skills I acquired in Germany, but being able to relate to other travelers and put the experience on my resume has helped me in so many more ways than knowing the ins and outs of industrial equipment ever could. Knowing I could live on my own in a new place and make connections there was a deciding factor in my choice to work in Oklahoma over the summer. From here, who knows where the road will take me? Wherever I end up, though, I am confident that with my past experience I will be able to thrive anywhere. And, if I may, a word of advice? If youââ¬â¢re young and looking for something to do over the summer, find an internship and take it. Donââ¬â¢t go into debt working for someone who isnââ¬â¢t paying you, but never underestimate the value of experience. You cannot know what the future holds, and the value of a good internship is immeasurable and applicable to any field. à Note from IEW: Although we certainly cherished the opportunities to work with these young adults this past summer, we are not able to offer internships every summer. Thanks for understanding.à Homeschooled through high school, Jacob Mauser currently attends Stetson University and is double majoring in English and Philosophy. In addition to reading literature and writing, he enjoys craft coffee and photography. He hopes to someday earn his Ph.D. and encourage a new generation of learners to reason, think, reflect, and write. Log in or register to post commentsJacob Mausers blog Log in or register to post comments
Sunday, May 17, 2020
Cognitive Behavioral Theory Of Cognitive Behavior Therapy
Theoretical Analysis Cognitive Behavioral Theory Several prestigious and monumental contributors commenced the development of cognitive behavioral therapy. The four main catalysts have been Albert Ellis, Aaron Beck, Judith Beck, and Donald Meichenbaum. Each of these trailblazers lead a different aspect of cognitive behavior therapies. While working through his own personal fears and anxieties, Albert Ellis developed what is now termed rational emotive behavior therapy (REBT) and is the first pathfinder of cognitive behavior therapy. He had been passionately involved in psychoanalysis, yet, he wanted faster results for his clients. He taught his clients to transfer negative thoughts about themselves to positive thoughts and saw this brought more expedient healing. REBT starts with the idea that people have both sound and unsound reasoning; then, in the end, teaches unconditional self-acceptance even through one s errors. Ellis REBT asserts that people s mental health issues come, not so much from an exterior problem, but from their perceptions and thoughts about a circumstance. The faulty beliefs are instilled when people are very young. Without realizing it, a person replays the messages in their mind throughout their life which creates behaviors in line with the inaccurate beliefs. Through cognitive restructuring, therapists assist clients in developing positive thoughts to replace their invalidating messages. (Corey, 2013). Aaron Beck is the primaryShow MoreRelatedTheories And Theories Of Counseling1051 Words à |à 5 PagesTheories in counseling gives future counselors the overall view of theories and why they are important. Theories serve as a guide for counselors and give justification for treatment given. A lack of theory would make it hard for a counselor to connect with their client and know what methods to use for a specific client. Theories sets the tone of how a counselor can affect change in their clientââ¬â¢s life. As a school counselor you would be dea ling with children with different types personalities andRead MoreCognitive Behavior Group Therapy Model Essay1284 Words à |à 6 PagesCognitive behavior group therapy is a highly structured an interactive form of psychotherapy. It is a widely used model. The cognitive behavior therapy is based on the social learning theory and characterized by many principles. The cognitive behavior group therapy model is used to treat a variety of emotional disorders. It is a problem-focused, short-term model of behavioral treatment that plays a role in helping clients understand that a person s thoughts have the ability to influence theirRead MoreWhat Is Clinical Psychology?1416 Words à |à 6 Pagesis Clinical Psychology? It is the branch of psychology that emphasizes on the assessment and treatment of mental illness, abnormal behavior, and psychiatric problems of a person. In this field, you get to correlate with complex human problems. Dealing with mental illness can specify even to psyc hological disorders, which are a ââ¬Å"harmful dysfunctionâ⬠in which behavior is judged to be: atypical, disturbing, maladaptive, and unjustifiable (Fahoum, 2017). Psychological disorders can be broken down intoRead MoreThe Principles Of Cognitive Behavioral Therapy1276 Words à |à 6 Pages Beck et al (1985) states that there are 10 principles of cognitive behavioral therapy. These principles are the foundation of the therapy. The principles discuss how the cognitive model is used as a basis for interventions. The principles go on to demonstrate that cognitive therapy is a brief intervention. Since the therapy is so brief it is important to stay on task in the therapeutic work being done. Since cognitive behavioral therapy is also time limited it needs to be structured. Another factorRead MoreCognitive Psychology : Cognitive Behavioral Therapy1447 Words à |à 6 PagesCognitive Behavioral Therapy Djiedjorm Doe (Dede) Middlesex Community College Cognitive behavioral therapy, commonly known as CBT, is a systematic process by which we learn to change our negative thought into more positive ones. CBT is a combination of two types of therapy, cognitive therapy and behavioral therapy. cognition is our thought, so cognitive behavioral therapy combines working with our thought process and changing our behavior at the same time. Cognitive behavioral therapistsRead MoreTreatment Models Chosen For Comparison1241 Words à |à 5 Pages Treatment Models Chosen for Comparison 1. Narrative Therapy the role of the therapist, views of people and their problems, and the approach for helping. Narrative therapy is a way to look at a personââ¬â¢s life story and their struggles from an outside looking in approach. The problems become separate from the individual. Narrative therapy helps the client examine their life story from a strengths perspective. Instead of focusing on the problems the worker helps the client identify their strengthsRead MorePsychodynamic Approach On Human Nature1108 Words à |à 5 Pagespsychodynamic, cognitive- behavioral, existential- humanistic, and postmodern approach. ââ¬Å"Psychodynamic approach sees human functioning based upon the interaction of drives and forces within the person, particularly unconscious, and between the different structures of the personality.â⬠(McLeod, 2007, para. 4). Psychodynamic approach uses conscious and unconscious forces to explain one s personality. Sigmund Freud is looked upon as one of the creators of this movement. ââ¬Å"Cognitive- behavioral approach,Read MoreNotes On Family Therapy Approache s1501 Words à |à 7 PagesRunning Head: Comparing Theories 1 Alan Bradley University of Phoenix MCC/ 04/17/2015 Comparing Theories 2 Family Therapy Approaches Paper Cognitive-Behavioral, Behavioral, Psychoanalytic, and Experiential are all forms of family therapy. Each of these therapies has many similarities and differencesRead MoreCognitive Psychology : Cognitive Behavioral Therapy1502 Words à |à 7 PagesCognitive Behavioral Therapy, in its most modern form, was developed in 1960 by Aaron T. Beck. However, CBT has an interesting history dating back to the 1920s in the United States and even earlier in other parts of the world. ââ¬Å"Precursors of certain fundamental aspects of CBT have been identified in various ancient philosophical traditions, particularly Stoicism. Stoic philosophers, particularly Epictetus, believed logic could be used to identify and discard false beliefs that lead to destructiveRead MoreCognitive Therapy for Depression1317 Words à |à 6 PagesCognitive Therapy for Depression Cognitive Therapy also known as (CT) is a form of psychotherapy that was developed by the psychiatrist Aaron T. Beck. This style of therapy is one that can change the unrealistic views and way of thinking of the client. This paper will discuss Cognitive Therapy for Depression on children, adults, the evidence that supports CT, and the disadvantages and advantages of CT. This paper will also discuss on how certain life experiences can cause psychological distress
Wednesday, May 6, 2020
Comparing Violence as a Motif in Stranger and Sailor Who...
Violence as a Motif in The Stranger and The Sailor Who Fell From Grace With The Sea In The Stranger by Albert Camus, and The Sailor Who Fell From Grace With the Sea by Yukio Mishima, violence is an important motif. This paper will attempt to show how comparisons exists in these books which aids the violence motif. Violence is concluded with murder or multiple murders in the above books. In The Stranger, Meursault, an absurd hero, shoots the Arab five times on the beach. He accounts for the scenario by telling the reader: My whole being tensed and I squeezed my hand around the revolver. The trigger gave; I felt the smooth underside of the butt; and there, in that noise, sharp and deafening at the same time, is where itâ⬠¦show more contentâ⬠¦Mishima goes on by stating: ââ¬Å"Noboru swung the kitten high above his head and slammed it at the log. The warm soft thing hurtled through the air in marvelous flight. But the sensation of down between his fingers lingeredâ⬠(Mishma 58). The kitten did not die on the first attempt and the Chief ordered Noboru to pick up the kitten and throw it against the log one more time. Mishima adds to the detail of the scene by telling the reader ââ¬Å"What Noboru lifted between two fingers now was no longer a kittenâ⬠(Mishima 58). On the second impact the defenseless kitten met its fate and died. The victim of the second murder that takes place in the book is Ryuji. Ryuji like Meursault is an absurd hero. His murder occurs near the sea. He is lured to t he murder scene by Noboru. His death was well planed by the Chief and the Gang and occurs when he takes a sip of tea laced with sleeping pills. Comparison of place setting where violence occurs exists in The Stranger and The Sailor Who Fell From Grace With The Sea. Meursault kills the Arab on an Algerian beach. For him the beach represented pleasure. He went swimming with Marie the day after his motherââ¬â¢s funeral. Ironically the sea also becomes the backdrop for the murder. He recalls before the murder occurs that ââ¬Å"The sea carried up a thick, fiery breathâ⬠(Camus 59). The setting for The Sailor Who Fell From Grace With The Sea is the port city of Yokohama, Japan. Ryujiââ¬â¢s murder takes place on an
Genetic heart engineering Essay Example For Students
Genetic heart engineering Essay Generic Heart Engineering:One problem in the medical field is the rate of heart transplants compared with the number of them needed. The disparity is too great for the medical community and needs to be solved. The biggest contributor to this predicament is the fact that hearts must be taken from recently deceased people and cannot be taken from living, willing donors because that would basically be suicide. Also, another problem with heart transplants is, after the statistical miracle of receiving a new heart, the foreign tissue could be rejected by ones own immune system. In addition to this, the recipient must take a gamut of medications to combat this effect. So how could each of these problems be eradicated in one foul swoop? This could all be solved with the bioengineering of a generic heart. First the term bioengineering must be defined. In my sense, this word means the manipulation of biology to yield good to man with the considerations of morals and ethics. With that in mind, Im sure engineering a heart fits into this category because it: definitely has potential for human good; manipulates biology in a way that helps mankind; and is not beyond the ethics of today: none would stop the production of a beneficial product with the capability to save thousands of lives. Now that we have more insight into bioengineering, we can begin to discuss the engineering of a heart. To engineer a heart, the pathways to its formation through stem cells must first be discovered through one genome line that is as healthy as possible (i.e. no signs of an genetic disorders, especially related to oncogenes, no family history of heart problems). Then a process could be made to grow a heart in vitro through the use of the right cell signaling, transcription factors and hormones. After this process is perfected, the genome could be screened again for any deleterious mutations that may have formed during this learning process. If any are to be found, then they could be excised through some method involving highly specific endonuclease (restriction factors) so only the specified site is affected. After this phase, the issue of foreign tissue rejection can be dealt with. The issue that comes up with all transplanted tissues is foreign organ rejection. This problem arises from the bodys specific immune system that can recognize self from nonself. It does this through various immune system molecules like antibodies, macrophages, B-cells and T-cells. But each of these finds a nonself tissue through foreign surface molecules. The most important surface molecule in this process is called a MHC (Major Histocompatibility Complex). These are a sort of I.D. card that the immune system recognizes. These are highly variable in humans, so unrelated people usually have compatibility problems in transplants. But this can be changed with a few steps. If the strain of DNA used for developing hearts has its MHC gene or genes culled, then a patient could donate DNA so scientists could find, duplicate and insert the patients MHC gene or genes. This would then allow scientist to grow hearts with the same specificity as the natural body. This then gives the medical commu nity to simply grow you a heart, no matter who you are. The one thing that must be stressed in this process is the genericness of its implementation. This process could be applied for any patient with heart problems. If your wondering why this doesnt already exist or why people arent researching this its because certain consequential procedures are missing. One such barrier to the implementation of this heart growing process is the lack of knowledge about cell differentiation. The restrictions on embryonic stem cells must be lifted so the mechanics of this can be further understood. Also, the highly specific restriction factors must be made or a more efficacious method of DNA manipulation must be formulated. But there is hope for both of these vital links because researchers are working day in and day out to find information on both of these. But until we have every step of this process, eat healthy, exercise and treat your heart right.
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